The main aim of this paper to establish the relations between forward, backward and central finite (divided) differences (that is discrete analog of the derivative) and partial & ordinary high-order derivatives of the polynomials.

Calculating the value of Ck ∈ {1, ∞} class of smoothness real-valued function's derivative in point of R+ in radius of convergence of its Taylor polynomial (or series), applying an analog of Newton's binomial theorem and q-difference operator. (P,q)-power difference introduced in section 5. Additionally, by means of Newton's interpolation formula, the discrete analog of Taylor series, interpolation using q-difference and p,q-power difference is shown.

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