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Rakam: Distributed Analytics API
Today, most of the “big data” applications needs to compute data in real-time since the Internet develops quite fast and the users expect the get reactions from the applications simultaneously. This rule is valid for almost all types of applications. When a user interacts with a commercial website by looking a product, the website should be able to show her related products for increasing its conversion rates. For a CRM application, the users should be able to solve their problem using that application. And most the time, these actions need aggregation computations. The aim of our project is to provide a high-performance scalable computational engine that is flexible and can be adapted to any type of applications. The system collects the events with collection API and continuously processes them on the fly with using pre-aggregation rules submitted by Analysis API.
Burak Emre Kabakcı
Engineering Fasciculin-II to treat Alzheimer's Disease Related Symptoms
Alzheimer’s disease is characterized by death of cholinergic neurons, which secrete the neurotransmitter acetylcholine. This results in a loss of the total amount of acetylcholine circulating in neural networks. Modern drugs target acetylcholinesterase so as to inhibit its function, allowing for increased transmission of acetylcholine in cholinergic synapses. The aim is that an increase in cholinergic activity leads to an increase in cognition. However, these drugs only bind temporarily and have consequential problems that make modern AChE inhibitors of little effect. The main goal of our project is to engineer a snake toxin, fasciculin-II, capable of crossing the blood brain barrier and inhibiting acetylcholinesterase with enough affinity that it increases cholinergic transmission without yielding toxic outcomes. This fasciculin binds to the peripheral acetylcholinesterase found in neuromuscular junctions and causes rapid twitching. Fasciculin-II binds to acetylcholinesterase very tightly with the use of many charged residues and hydrophobic residues and we would like to optimize this interaction so that it may serve a therapeutic purpose in patients of AD.
Inleiding tot R
Dit is een Nederlandstalige bijdrage vanwege Ludo Poelaert, UGent.
In deze korte tekst wordt een inleiding tot de taal R gegeven.
U mag de tekst vrij gebruiken onder het Creative Commons CC BY 4.0 .
Professor Ludo Poelaert
The Entity Registry System. From Concept to Deployment
The entity registry system (ERS) is a decentralized entity registry that can be used to replace the Web as a platform for publishing linked data when the latter is not available. In developing countries, where off-line is the default mode of operation, centralized linked data solutions fail to address the needs of the communities. Although the features are mostly completed, the system is not yet ready for deployment. This project aims to provide extensive tests and scalability investigations that would make it ready for a real scenario.
Constraints for BETYdb
Constraints on the Biofuel Ecophysiological Traits and Yields Database to ensure its logical integrity.
Scott Rohde and David LeBauer
The summation of all prime numbers
A proof is given that the summation of all prime numbers can be assigned the value of 13/12, as well as values that can be assigned to the summation of all multiples and all odd multiples.
Fernando Franco Félix
Pérdidas de energía por fricción
EDGAR ORLANDO LADINO MORENO