![Limiting Sample Damage In Laser Diagnostics](https://writelatex.s3.amazonaws.com/published_ver/725.jpeg?X-Amz-Expires=14400&X-Amz-Date=20240727T011453Z&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIAWJBOALPNFPV7PVH5/20240727/us-east-1/s3/aws4_request&X-Amz-SignedHeaders=host&X-Amz-Signature=a3503a4fbcd0075047bac27948267db7c383da0664746e5b2d99b71e027c43fb)
Limiting Sample Damage In Laser Diagnostics
Author
Toby Toller
Last Updated
10 years ago
License
Creative Commons CC BY 4.0
Abstract
Tests conducted comparing the effect exposure of Paracetamol to a laser with oven heating a sample to a temperature above its melting point, 169 degrees Celsius showed similarities. This implies that the primary cause of sample damage during Raman spectroscopy is heating. It was found that inserting a piece of glass between the sample and the microscope lens dramatically reduced the ability of the laser to damage samples. Computer models indicate that rotating a sample at 8 rotations per minute could be an effective method of limiting sample damage, and is a potential alternative to active cooling if this becomes financially and logistically viable in industry. Active sample cooling was investigated, but results proved inconclusive. This is a key area for any future research on the topic.
![Limiting Sample Damage In Laser Diagnostics](https://writelatex.s3.amazonaws.com/published_ver/725.jpeg?X-Amz-Expires=14400&X-Amz-Date=20240727T011453Z&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIAWJBOALPNFPV7PVH5/20240727/us-east-1/s3/aws4_request&X-Amz-SignedHeaders=host&X-Amz-Signature=a3503a4fbcd0075047bac27948267db7c383da0664746e5b2d99b71e027c43fb)